Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.000853 | uM | 10872.153 | 1.0397 | 1.0507 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10872.153 | 0.9963 | 0.9953 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10872.153 | 0.9356 | 0.9163 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.107 | uM | 10872.153 | 1.0119 | 1.0153 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.533 | uM | 10872.153 | 0.9426 | 0.9256 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 2.67 | uM | 10872.153 | 0.8968 | 0.8649 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 13.3 | uM | 10872.153 | 0.4987 | 0.2794 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 66.7 | uM | 10872.153 | 0.0147 | -0.8670 | 1.5576 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12523.165 | 1.0042 | 1.0082 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12523.165 | 0.9883 | 0.9771 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12523.165 | 1.0048 | 1.0094 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12523.165 | 1.0172 | 1.0335 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.107 | uM | 12523.165 | 0.9747 | 0.9506 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 0.533 | uM | 12523.165 | 1.0112 | 1.0218 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 2.67 | uM | 12523.165 | 0.9195 | 0.8428 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 13.3 | uM | 12523.165 | 0.6327 | 0.2795 | 1.0249 | |
| HCC1569 | HER2amp | Basal A | Sigma A6730 | AKT | AKT | 66.7 | uM | 12523.165 | 0.2346 | -0.5139 | 1.0249 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12239.165 | 0.9953 | 0.9955 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12239.165 | 0.9784 | 0.9790 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12239.165 | 1.0070 | 1.0067 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12239.165 | 1.0255 | 1.0245 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.107 | uM | 12239.165 | 0.9965 | 0.9966 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.533 | uM | 12239.165 | 0.9598 | 0.9608 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 2.67 | uM | 12239.165 | 0.9454 | 0.9465 | 2.0705 | |
| HCC1806 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 13.3 | uM | 12239.165 | 0.3744 | 0.2445 | 2.0705 |