Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10816.147 | 1.0861 | 1.2401 | 0.7283 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10816.147 | 1.0579 | 1.1606 | 0.7283 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10816.147 | 0.9784 | 0.9410 | 0.7283 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10816.147 | 0.5080 | -0.2108 | 0.7283 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10816.147 | 0.0304 | -0.9835 | 0.7283 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10816.147 | 0.0549 | -0.9628 | 0.7283 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12319.147 | 0.8571 | 0.7547 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12319.147 | 0.8141 | 0.6796 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12319.147 | 0.9838 | 0.9725 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12319.147 | 0.8238 | 0.6966 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12319.147 | 1.0088 | 1.0149 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12319.147 | 0.8193 | 0.6888 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12319.147 | 0.3839 | -0.1125 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12319.147 | 0.0337 | -0.8875 | 1.1783 | |
| LY2 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12319.147 | 0.0590 | -0.8188 | 1.1783 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12580.147 | 0.9941 | 0.9947 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12580.147 | 0.9960 | 0.9964 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12580.147 | 0.9921 | 0.9929 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12580.147 | 0.9968 | 0.9972 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12580.147 | 0.9180 | 0.9249 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12580.147 | 0.6515 | 0.6512 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12580.147 | 0.2216 | 0.0192 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12580.147 | 0.0456 | -0.4974 | 2.2358 | |
| MB 157 | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12580.147 | 0.0127 | -0.7159 | 2.2358 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 11056.147 | 1.0153 | 1.0109 | 2.7832 |