Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Oxamflatin | HDAC | HDAC | 0.533 | uM | 11854.147 | 0.9671 | 0.9477 | 1.2634 | |
| BT-20 | TNBC | Basal A | Oxamflatin | HDAC | HDAC | 2.67 | uM | 11854.147 | 0.7922 | 0.6633 | 1.2634 | |
| BT-20 | TNBC | Basal A | Oxamflatin | HDAC | HDAC | 13.3 | uM | 11854.147 | 0.3852 | -0.0600 | 1.2634 | |
| BT-20 | TNBC | Basal A | Oxamflatin | HDAC | HDAC | 66.7 | uM | 11854.147 | 0.0671 | -0.7642 | 1.2634 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12056.147 | 0.9067 | 0.7784 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12056.147 | 0.8885 | 0.7358 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12056.147 | 0.8799 | 0.7157 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12056.147 | 0.8187 | 0.5736 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12056.147 | 0.7325 | 0.3773 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12056.147 | 0.6151 | 0.1171 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12056.147 | 0.2609 | -0.6003 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12056.147 | 0.0537 | -0.9399 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12056.147 | 0.0278 | -0.9727 | 0.8344 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12178.147 | 1.0570 | 1.2009 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12178.147 | 0.9892 | 0.9627 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12178.147 | 0.9610 | 0.8672 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12178.147 | 0.9650 | 0.8808 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12178.147 | 0.8503 | 0.5118 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12178.147 | 0.8324 | 0.4574 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12178.147 | 0.5281 | -0.3355 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12178.147 | 0.0941 | -0.9661 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12178.147 | 0.0526 | -0.9876 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12291.147 | 0.9369 | 0.7933 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12291.147 | 0.8944 | 0.6595 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12291.147 | 1.0158 | 1.0530 | 0.5980 |