Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10999.155 | 1.0235 | 1.0641 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10999.155 | 1.0075 | 1.0204 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10999.155 | 1.0075 | 1.0204 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10999.155 | 1.0724 | 1.1991 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10999.155 | 1.0724 | 1.1991 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10999.155 | 0.9900 | 0.9729 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10999.155 | 0.9900 | 0.9729 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10999.155 | 1.0972 | 1.2681 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10999.155 | 1.0972 | 1.2681 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10999.155 | 1.0008 | 1.0022 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10999.155 | 1.0008 | 1.0022 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10999.155 | 1.0623 | 1.1709 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10999.155 | 1.0623 | 1.1709 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10999.155 | 0.9640 | 0.9030 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10999.155 | 0.9640 | 0.9030 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10999.155 | 1.0419 | 1.1144 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10999.155 | 1.0419 | 1.1144 | 0.7370 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12379.155 | 0.9829 | 0.9111 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12379.155 | 0.9829 | 0.9111 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12379.155 | 1.0416 | 1.2269 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12379.155 | 1.0416 | 1.2269 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12379.155 | 1.0174 | 1.0929 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12379.155 | 1.0174 | 1.0929 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12379.155 | 1.0024 | 1.0128 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12379.155 | 1.0024 | 1.0128 | 0.3793 |