Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12379.155 | 0.9884 | 0.9395 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12379.155 | 0.9884 | 0.9395 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12379.155 | 1.0181 | 1.0969 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12379.155 | 1.0181 | 1.0969 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12379.155 | 1.0151 | 1.0808 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12379.155 | 1.0151 | 1.0808 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12379.155 | 0.9633 | 0.8120 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12379.155 | 0.9633 | 0.8120 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12379.155 | 0.9243 | 0.6251 | 0.3793 | |
| MDA-MB-361 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12379.155 | 0.9243 | 0.6251 | 0.3793 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10938.155 | 1.1519 | 1.6068 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10938.155 | 1.1519 | 1.6068 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10938.155 | 1.1433 | 1.5705 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10938.155 | 1.1433 | 1.5705 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10938.155 | 1.2423 | 2.0036 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10938.155 | 1.2423 | 2.0036 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10938.155 | 1.1806 | 1.7301 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10938.155 | 1.1806 | 1.7301 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10938.155 | 1.3111 | 2.3224 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10938.155 | 1.3111 | 2.3224 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10938.155 | 0.9326 | 0.7548 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10938.155 | 0.9326 | 0.7548 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10938.155 | 1.3886 | 2.7003 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10938.155 | 1.3886 | 2.7003 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10938.155 | 1.3365 | 2.4442 | 0.5336 |