Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10938.155 | 1.3365 | 2.4442 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10938.155 | 1.3906 | 2.7102 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10938.155 | 1.3906 | 2.7102 | 0.5336 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12333.155 | 1.0091 | 1.0314 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12333.155 | 1.0091 | 1.0314 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12333.155 | 1.0013 | 1.0043 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12333.155 | 1.0013 | 1.0043 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12333.155 | 0.9640 | 0.8772 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12333.155 | 0.9640 | 0.8772 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12333.155 | 0.9971 | 0.9901 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12333.155 | 0.9971 | 0.9901 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12333.155 | 1.0163 | 1.0567 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12333.155 | 1.0163 | 1.0567 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12333.155 | 0.9649 | 0.8802 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12333.155 | 0.9649 | 0.8802 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12333.155 | 0.9828 | 0.9409 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12333.155 | 0.9828 | 0.9409 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12333.155 | 0.9105 | 0.7011 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12333.155 | 0.9105 | 0.7011 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12333.155 | 0.9507 | 0.8328 | 0.5790 | |
| MDA-MB-415 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12333.155 | 0.9507 | 0.8328 | 0.5790 | |
| MDA-MB-436 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0000853 | uM | 7898.029 | 1.2176 | 1.6360 | 0.7130 | |
| MDA-MB-436 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0000853 | uM | 7898.029 | 1.2176 | 1.6360 | 0.7130 | |
| MDA-MB-436 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 7898.029 | 1.4608 | 2.4031 | 0.7130 | |
| MDA-MB-436 | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 7898.029 | 1.4608 | 2.4031 | 0.7130 |