Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.267 | uM | 12580.155 | 0.8505 | 0.8600 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.267 | uM | 12580.155 | 0.8505 | 0.8600 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 1.33 | uM | 12580.155 | 0.9659 | 0.9692 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 1.33 | uM | 12580.155 | 0.9659 | 0.9692 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 6.67 | uM | 12580.155 | 0.7569 | 0.7653 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 6.67 | uM | 12580.155 | 0.7569 | 0.7653 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 33.3 | uM | 12580.155 | 0.3651 | 0.2734 | 2.2315 | |
MB 157 | Unknown | Unknown | PD184352 | MEK | MAPK | 33.3 | uM | 12580.155 | 0.3651 | 0.2734 | 2.2315 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.0000853 | uM | 11056.155 | 0.9341 | 0.9540 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.0000853 | uM | 11056.155 | 0.9341 | 0.9540 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 11056.155 | 0.9707 | 0.9798 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.000427 | uM | 11056.155 | 0.9707 | 0.9798 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.00213 | uM | 11056.155 | 0.9695 | 0.9790 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.00213 | uM | 11056.155 | 0.9695 | 0.9790 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.0107 | uM | 11056.155 | 0.9836 | 0.9887 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.0107 | uM | 11056.155 | 0.9836 | 0.9887 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.0533 | uM | 11056.155 | 0.8426 | 0.8863 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.0533 | uM | 11056.155 | 0.8426 | 0.8863 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.267 | uM | 11056.155 | 0.6789 | 0.7522 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 0.267 | uM | 11056.155 | 0.6789 | 0.7522 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 1.33 | uM | 11056.155 | 0.5576 | 0.6382 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 1.33 | uM | 11056.155 | 0.5576 | 0.6382 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 6.67 | uM | 11056.155 | 0.4036 | 0.4669 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 6.67 | uM | 11056.155 | 0.4036 | 0.4669 | 2.9269 | |
MCF 10A | NM | Basal B | PD184352 | MEK | MAPK | 33.3 | uM | 11056.155 | 0.1958 | 0.1457 | 2.9269 |