Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7527.065 | 0.9339 | 0.9271 | 1.8429 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7528.065 | 0.9829 | 0.9693 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7528.065 | 1.0190 | 1.0342 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7528.065 | 0.9311 | 0.8756 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7528.065 | 1.0373 | 1.0669 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7528.065 | 0.9258 | 0.8661 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7528.065 | 0.9639 | 0.9350 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7528.065 | 0.9215 | 0.8584 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7528.065 | 0.9951 | 0.9911 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7528.065 | 0.9706 | 0.9471 | 1.1128 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 9044.065 | 1.0196 | 1.0665 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 9044.065 | 1.0038 | 1.0128 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 9044.065 | 1.0358 | 1.1218 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 9044.065 | 1.0495 | 1.1695 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 9044.065 | 1.0270 | 1.0916 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 9044.065 | 1.0266 | 1.0902 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 9044.065 | 0.9644 | 0.8816 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 9044.065 | 1.0437 | 1.1493 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 9044.065 | 0.9589 | 0.8636 | 0.5944 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 10381.065 | 1.0761 | 1.1220 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 10381.065 | 1.0387 | 1.0623 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 10381.065 | 0.9949 | 0.9917 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 10381.065 | 1.0440 | 1.0708 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 10381.065 | 1.0585 | 1.0939 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 10381.065 | 0.9660 | 0.9450 | 1.2390 |