Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.0243 | uM | 7523.065 | 1.0576 | 1.1515 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.121 | uM | 7523.065 | 1.0153 | 1.0399 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.606 | uM | 7523.065 | 1.0584 | 1.1536 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 3.03 | uM | 7523.065 | 1.0293 | 1.0767 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 15.2 | uM | 7523.065 | 1.0022 | 1.0057 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 75.8 | uM | 7523.065 | 1.0132 | 1.0344 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 379 | uM | 7523.065 | 1.1193 | 1.3166 | 0.7668 | |
| MX1 | Unknown | Unknown | PS-1145 | IKK | NFKB | 1890 | uM | 7523.065 | 1.1032 | 1.2734 | 0.7668 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7526.065 | 0.9334 | 0.9135 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7526.065 | 0.9572 | 0.9447 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7526.065 | 0.9133 | 0.8869 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7526.065 | 0.9627 | 0.9517 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7526.065 | 0.8269 | 0.7703 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7526.065 | 0.9637 | 0.9531 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7526.065 | 0.7981 | 0.7306 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7526.065 | 0.9633 | 0.9526 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7526.065 | 1.0114 | 1.0145 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7527.065 | 1.0435 | 1.0467 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7527.065 | 0.9622 | 0.9586 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7527.065 | 0.9377 | 0.9314 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7527.065 | 0.9681 | 0.9651 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7527.065 | 0.9790 | 0.9771 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7527.065 | 0.8926 | 0.8805 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7527.065 | 0.9842 | 0.9828 | 1.8429 | |
| SK-BR-3 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7527.065 | 0.9637 | 0.9603 | 1.8429 |