Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7477.065 | 1.9549 | 3.6768 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7477.065 | 1.1641 | 1.4247 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7477.065 | 1.5936 | 2.6098 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7477.065 | 2.0163 | 3.8638 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7477.065 | 3.5926 | 9.1125 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7477.065 | 4.1296 | 11.0648 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 10380.065 | 1.0516 | 1.0686 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 10380.065 | 1.0257 | 1.0343 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 10380.065 | 1.0359 | 1.0478 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 10380.065 | 1.0693 | 1.0919 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 10380.065 | 1.1098 | 1.1446 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 10380.065 | 1.0275 | 1.0367 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 10380.065 | 1.1868 | 1.2434 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 10380.065 | 1.2859 | 1.3672 | 1.4916 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 10380.065 | 1.2997 | 1.3842 | 1.4916 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.00485 | uM | 7482.065 | 1.0312 | 1.0277 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.0243 | uM | 7482.065 | 0.9749 | 0.9774 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.121 | uM | 7482.065 | 0.9849 | 0.9865 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 0.606 | uM | 7482.065 | 0.9354 | 0.9413 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 3.03 | uM | 7482.065 | 0.9928 | 0.9936 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 15.2 | uM | 7482.065 | 0.9762 | 0.9786 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 75.8 | uM | 7482.065 | 1.0784 | 1.0685 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 379 | uM | 7482.065 | 0.9723 | 0.9751 | 2.2390 | |
| MB 157 | Unknown | Unknown | PS-1145 | IKK | NFKB | 1890 | uM | 7482.065 | 0.9355 | 0.9413 | 2.2390 | |
| MCF 10A | NM | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7483.065 | 1.0272 | 1.0177 | 3.0487 |