Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7443.065 | 1.1306 | 1.2986 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7443.065 | 1.1296 | 1.2964 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7443.065 | 1.1405 | 1.3216 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7443.065 | 1.0953 | 1.2174 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7444.065 | 1.0087 | 1.0235 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7444.065 | 1.0176 | 1.0476 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7444.065 | 1.0372 | 1.1010 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7444.065 | 1.0671 | 1.1830 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7444.065 | 1.0256 | 1.0694 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7444.065 | 1.0243 | 1.0658 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7444.065 | 1.0586 | 1.1595 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7444.065 | 1.1353 | 1.3730 | 0.7419 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7444.065 | 1.0354 | 1.0960 | 0.7419 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7448.065 | 0.9750 | 0.9807 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7448.065 | 0.9927 | 0.9944 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7448.065 | 1.0178 | 1.0136 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7448.065 | 1.0373 | 1.0282 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7448.065 | 0.9961 | 0.9970 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7448.065 | 1.0247 | 1.0188 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7448.065 | 0.9815 | 0.9858 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7448.065 | 1.0325 | 1.0247 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7448.065 | 0.8909 | 0.9134 | 2.6104 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7449.065 | 1.0770 | 1.0728 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7449.065 | 1.0623 | 1.0591 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7449.065 | 0.9635 | 0.9645 | 2.0765 |