Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10999.144 | 1.0047 | 1.0138 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10999.144 | 1.0084 | 1.0245 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10999.144 | 0.9988 | 0.9966 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10999.144 | 1.0197 | 1.0577 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10999.144 | 1.0422 | 1.1239 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10999.144 | 1.0117 | 1.0342 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10999.144 | 0.9949 | 0.9851 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10999.144 | 0.9504 | 0.8575 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12379.168 | 1.0519 | 1.2289 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12379.168 | 1.0542 | 1.2392 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12379.168 | 1.0503 | 1.2217 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12379.168 | 1.0570 | 1.2519 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12379.168 | 1.0955 | 1.4312 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12379.168 | 1.0610 | 1.2702 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12379.168 | 1.0227 | 1.0983 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12379.168 | 1.0378 | 1.1653 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12379.168 | 1.0599 | 1.2652 | 0.4672 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10938.144 | 0.8738 | 0.7762 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10938.144 | 0.8519 | 0.7370 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10938.144 | 0.9963 | 0.9935 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10938.144 | 0.8749 | 0.7781 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10938.144 | 0.8381 | 0.7122 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10938.144 | 0.8671 | 0.7642 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10938.144 | 0.9193 | 0.8574 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10938.144 | 0.7812 | 0.6096 | 1.1369 |