Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10938.144 | 0.7013 | 0.4637 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12333.168 | 0.9756 | 0.9167 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12333.168 | 0.9702 | 0.8986 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12333.168 | 1.0158 | 1.0548 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12333.168 | 1.0512 | 1.1793 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12333.168 | 0.9514 | 0.8358 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12333.168 | 1.0151 | 1.0523 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12333.168 | 0.9328 | 0.7745 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12333.168 | 0.4279 | -0.5354 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12333.168 | 0.0131 | -0.9988 | 0.5815 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12414.168 | 0.9820 | 0.9701 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12414.168 | 0.9664 | 0.9441 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12414.168 | 0.9699 | 0.9499 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12414.168 | 0.9423 | 0.9039 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12414.168 | 0.9687 | 0.9481 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12414.168 | 0.9663 | 0.9440 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12414.168 | 0.8525 | 0.7522 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12414.168 | 0.7434 | 0.5643 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12414.168 | 0.8130 | 0.6847 | 1.2069 | |
| MX1 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10644.144 | 1.0171 | 1.0644 | 0.5357 | |
| MX1 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10644.144 | 0.9377 | 0.7736 | 0.5357 | |
| MX1 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10644.144 | 1.0123 | 1.0463 | 0.5357 | |
| MX1 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10644.144 | 0.9528 | 0.8274 | 0.5357 | |
| MX1 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10644.144 | 0.9776 | 0.9172 | 0.5357 | |
| MX1 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10644.144 | 0.9934 | 0.9755 | 0.5357 |