Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11055.144 | 0.9275 | 0.9120 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11055.144 | 1.0245 | 1.0292 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11055.144 | 0.9478 | 0.9369 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11055.144 | 0.9329 | 0.9186 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11055.144 | 0.9771 | 0.9725 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 11055.144 | 0.9928 | 0.9913 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 11055.144 | 0.8677 | 0.8373 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 11055.144 | 0.8212 | 0.7776 | 1.6716 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10996.144 | 0.9693 | 0.8819 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10996.144 | 0.9434 | 0.7848 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10996.144 | 0.9567 | 0.8342 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10996.144 | 0.9711 | 0.8885 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10996.144 | 0.9740 | 0.8995 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10996.144 | 1.0298 | 1.1182 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10996.144 | 0.9302 | 0.7364 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10996.144 | 0.9363 | 0.7584 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10996.144 | 0.8550 | 0.4725 | 0.5116 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12192.144 | 0.9250 | 0.7483 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12192.144 | 1.0432 | 1.1514 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12192.144 | 0.9303 | 0.7656 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12192.144 | 0.9464 | 0.8185 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12192.144 | 0.9222 | 0.7394 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12192.144 | 0.9749 | 0.9141 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 12192.144 | 0.9921 | 0.9727 | 0.5798 | |
| HCC2185 | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 12192.144 | 0.8806 | 0.6063 | 0.5798 |