Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10644.142 | 0.9780 | 0.9157 | 0.5163 | |
| MX1 | Unknown | Unknown | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10644.142 | 0.9966 | 0.9869 | 0.5163 | |
| MX1 | Unknown | Unknown | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10644.142 | 0.9764 | 0.9097 | 0.5163 | |
| MX1 | Unknown | Unknown | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10644.142 | 1.0052 | 1.0201 | 0.5163 | |
| MX1 | Unknown | Unknown | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10644.142 | 0.9829 | 0.9342 | 0.5163 | |
| MX1 | Unknown | Unknown | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10644.142 | 0.9626 | 0.8577 | 0.5163 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10520.142 | 1.1619 | 1.0967 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10520.142 | 0.9639 | 0.9770 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10520.142 | 0.8670 | 0.9121 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10520.142 | 1.1090 | 1.0662 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10520.142 | 1.2629 | 1.1525 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10520.142 | 1.0829 | 1.0508 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10520.142 | 1.4344 | 1.2405 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10520.142 | 1.1310 | 1.0790 | 3.1766 | |
| SUM159PT | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10520.142 | 1.1507 | 1.0903 | 3.1766 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10579.142 | 1.0577 | 1.1105 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10579.142 | 0.9672 | 0.9371 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10579.142 | 1.0004 | 1.0007 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10579.142 | 1.0033 | 1.0064 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10579.142 | 1.1010 | 1.1931 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10579.142 | 0.9948 | 0.9901 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10579.142 | 1.0296 | 1.0566 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10579.142 | 1.0471 | 1.0902 | 1.0435 | |
| SUM225CWN | HER2amp | Basal A | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10579.142 | 1.1098 | 1.2099 | 1.0435 | |
| UACC-812 | HER2amp | Luminal | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10580.142 | 1.0355 | 1.0886 | 0.8039 |