Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Ribavirin | 0.4 | uM | 15354.211 | 0.9517 | 0.9519 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 2 | uM | 15354.211 | 0.9283 | 0.9281 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 10 | uM | 15354.211 | 0.8680 | 0.8654 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 50 | uM | 15354.211 | 0.7313 | 0.7146 | 2.0320 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 0.000128 | uM | 15394.211 | 0.9867 | 0.9854 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 0.00064 | uM | 15394.211 | 0.9560 | 0.9514 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 0.0032 | uM | 15394.211 | 0.9725 | 0.9698 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 0.016 | uM | 15394.211 | 0.9707 | 0.9678 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 0.08 | uM | 15394.211 | 1.1156 | 1.1233 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 0.4 | uM | 15394.211 | 1.1029 | 1.1100 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 2 | uM | 15394.211 | 1.0863 | 1.0926 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 10 | uM | 15394.211 | 0.8457 | 0.8250 | 1.8299 | |||
| MCF7 | HR+ | Luminal | Ribavirin | 50 | uM | 15394.211 | 0.5967 | 0.5083 | 1.8299 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 0.000128 | uM | 15355.211 | 0.9495 | 0.9045 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 0.00064 | uM | 15355.211 | 0.8867 | 0.7852 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 0.0032 | uM | 15355.211 | 0.8726 | 0.7584 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 0.016 | uM | 15355.211 | 0.8712 | 0.7558 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 0.08 | uM | 15355.211 | 0.9129 | 0.8351 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 0.4 | uM | 15355.211 | 0.9792 | 0.9606 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 2 | uM | 15355.211 | 1.0018 | 1.0033 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 10 | uM | 15355.211 | 1.0184 | 1.0347 | 1.0584 | |||
| MDA-MB-134-VI | HR+ | Luminal | Ribavirin | 50 | uM | 15355.211 | 0.9741 | 0.9510 | 1.0584 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 0.000128 | uM | 15321.211 | 1.0063 | 1.0046 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 0.00064 | uM | 15321.211 | 0.9533 | 0.9654 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 0.0032 | uM | 15321.211 | 0.9994 | 0.9996 | 2.7437 |