Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.0107 | uM | 5910.069 | 0.7180 | 0.8117 | 3.3504 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.0533 | uM | 5910.069 | 0.6653 | 0.7710 | 3.3504 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.267 | uM | 5910.069 | 0.6677 | 0.7729 | 3.3504 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 1.33 | uM | 5910.069 | 0.5945 | 0.7124 | 3.3504 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 6.67 | uM | 5910.069 | 0.6106 | 0.7262 | 3.3504 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 33.3 | uM | 5910.069 | 0.5610 | 0.6831 | 3.3504 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.000427 | uM | 9024.068 | 0.9371 | 0.9550 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.00213 | uM | 9024.068 | 0.7775 | 0.8310 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.0107 | uM | 9024.068 | 0.7002 | 0.7650 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.0533 | uM | 9024.068 | 0.6698 | 0.7378 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.267 | uM | 9024.068 | 0.6473 | 0.7171 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 1.33 | uM | 9024.068 | 0.6237 | 0.6949 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 6.67 | uM | 9024.068 | 0.5865 | 0.6587 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 33.3 | uM | 9024.068 | 0.0284 | -0.4266 | 2.8519 | |
| BT-549 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 167 | uM | 9024.068 | 0.0065 | -0.6584 | 2.8519 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 5911.068 | 1.0335 | 1.0678 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 5911.068 | 0.9567 | 0.9123 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 5911.068 | 0.7793 | 0.5535 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 5911.068 | 0.6193 | 0.2309 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 5911.068 | 0.6110 | 0.2143 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 5911.068 | 0.5485 | 0.0886 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 5911.068 | 0.5806 | 0.1530 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 5911.068 | 0.5390 | 0.0694 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 167 | uM | 5911.068 | 0.5211 | 0.0336 | 0.9873 | |
| CAMA-1 | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 5912.069 | 1.0214 | 1.0447 | 0.9582 |