Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 0.016 | uM | 15321.211 | 0.9771 | 0.9832 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 0.08 | uM | 15321.211 | 1.0341 | 1.0246 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 0.4 | uM | 15321.211 | 0.9662 | 0.9751 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 2 | uM | 15321.211 | 0.8832 | 0.9115 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 10 | uM | 15321.211 | 0.7336 | 0.7865 | 2.7437 | |||
| MDA-MB-157 | TNBC | Basal B | Ribavirin | 50 | uM | 15321.211 | 0.5270 | 0.5835 | 2.7437 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 0.000128 | uM | 15396.211 | 0.9741 | 0.9433 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 0.00064 | uM | 15396.211 | 0.9461 | 0.8822 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 0.0032 | uM | 15396.211 | 0.9409 | 0.8710 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 0.016 | uM | 15396.211 | 0.9345 | 0.8570 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 0.08 | uM | 15396.211 | 1.0371 | 1.0814 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 0.4 | uM | 15396.211 | 1.0624 | 1.1369 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 2 | uM | 15396.211 | 1.0761 | 1.1671 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 10 | uM | 15396.211 | 0.9905 | 0.9792 | 0.9137 | |||
| MDA-MB-361 | HER2amp | Luminal | Ribavirin | 50 | uM | 15396.211 | 0.8383 | 0.6490 | 0.9137 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 0.000128 | uM | 15325.211 | 1.0418 | 1.0740 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 0.00064 | uM | 15325.211 | 1.0157 | 1.0278 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 0.0032 | uM | 15325.211 | 1.0241 | 1.0426 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 0.016 | uM | 15325.211 | 0.9784 | 0.9617 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 0.08 | uM | 15325.211 | 1.0599 | 1.1057 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 0.4 | uM | 15325.211 | 1.0371 | 1.0656 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 2 | uM | 15325.211 | 0.9325 | 0.8799 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 10 | uM | 15325.211 | 0.9193 | 0.8563 | 1.1289 | |||
| MDA-MB-415 | HR+ | Luminal | Ribavirin | 50 | uM | 15325.211 | 0.7885 | 0.6204 | 1.1289 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 0.000128 | uM | 15398.211 | 0.9669 | 0.9376 | 1.0628 |