Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 0.00064 | uM | 15398.211 | 0.9306 | 0.8691 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 0.0032 | uM | 15398.211 | 0.9703 | 0.9441 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 0.016 | uM | 15398.211 | 0.9750 | 0.9529 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 0.08 | uM | 15398.211 | 1.0272 | 1.0511 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 0.4 | uM | 15398.211 | 1.0456 | 1.0857 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 2 | uM | 15398.211 | 1.0781 | 1.1467 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 10 | uM | 15398.211 | 1.0344 | 1.0646 | 1.0628 | |||
| MDA-MB-453 | TNBC | Luminal | Ribavirin | 50 | uM | 15398.211 | 0.9460 | 0.8982 | 1.0628 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 0.000128 | uM | 15356.211 | 0.9615 | 0.9411 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 0.00064 | uM | 15356.211 | 0.9265 | 0.8868 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 0.0032 | uM | 15356.211 | 0.9778 | 0.9660 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 0.016 | uM | 15356.211 | 0.9834 | 0.9746 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 0.08 | uM | 15356.211 | 1.0362 | 1.0550 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 0.4 | uM | 15356.211 | 1.0264 | 1.0401 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 2 | uM | 15356.211 | 0.9772 | 0.9652 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 10 | uM | 15356.211 | 0.9443 | 0.9145 | 1.3112 | |||
| SK-BR-3 | HER2amp | Luminal | Ribavirin | 50 | uM | 15356.211 | 0.7133 | 0.5457 | 1.3112 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 0.000128 | uM | 15401.211 | 1.0085 | 1.0417 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 0.00064 | uM | 15401.211 | 0.9987 | 0.9935 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 0.0032 | uM | 15401.211 | 0.9663 | 0.8386 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 0.016 | uM | 15401.211 | 0.8533 | 0.3556 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 0.08 | uM | 15401.211 | 0.9971 | 0.9859 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 0.4 | uM | 15401.211 | 0.9956 | 0.9784 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 2 | uM | 15401.211 | 1.0533 | 1.2716 | 0.4079 | |||
| SUM1315MO2 | TNBC | Basal B | Ribavirin | 10 | uM | 15401.211 | 1.0573 | 1.2926 | 0.4079 |