Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Sirolimus | MTOR | MTOR | 167 | uM | 7429.068 | 0.7098 | 0.7212 | 2.2830 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7809.068 | 0.8371 | 0.8037 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7809.068 | 0.8555 | 0.8266 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7809.068 | 0.6919 | 0.6147 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7809.068 | 0.6260 | 0.5233 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.267 | uM | 7809.068 | 0.6114 | 0.5026 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 1.33 | uM | 7809.068 | 0.6505 | 0.5578 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 6.67 | uM | 7809.068 | 0.7023 | 0.6287 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 33.3 | uM | 7809.068 | 0.5265 | 0.3777 | 1.7208 | |
| HCC1143 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 167 | uM | 7809.068 | 0.5107 | 0.3535 | 1.7208 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 7432.069 | 1.0196 | 1.0402 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7432.069 | 0.9119 | 0.8191 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7432.069 | 0.7692 | 0.5272 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7432.069 | 0.6475 | 0.2793 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7432.069 | 0.6085 | 0.2001 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.267 | uM | 7432.069 | 0.5537 | 0.0891 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 1.33 | uM | 7432.069 | 0.5106 | 0.0020 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 6.67 | uM | 7432.069 | 0.4778 | -0.0641 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 33.3 | uM | 7432.069 | 0.3962 | -0.2280 | 0.9727 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 7433.069 | 1.0236 | 1.0457 | 1.0307 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7433.069 | 0.9997 | 0.9993 | 1.0307 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7433.069 | 0.8748 | 0.7567 | 1.0307 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7433.069 | 0.7922 | 0.5955 | 1.0307 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7433.069 | 0.7389 | 0.4912 | 1.0307 | |
| HCC1187 | TNBC | Basal A | Sirolimus | MTOR | MTOR | 0.267 | uM | 7433.069 | 0.7275 | 0.4688 | 1.0307 |