Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Ribavirin | 10 | uM | 15391.211 | 1.0596 | 1.0923 | 1.2835 | |||
| LY2 | HR+ | Luminal | Ribavirin | 50 | uM | 15391.211 | 0.9824 | 0.9725 | 1.2835 | |||
| MCF 10A | NM | Basal B | Ribavirin | 0.000128 | uM | 15392.211 | 0.8558 | 0.8977 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 0.00064 | uM | 15392.211 | 0.8560 | 0.8979 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 0.0032 | uM | 15392.211 | 0.8774 | 0.9137 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 0.016 | uM | 15392.211 | 0.8717 | 0.9096 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 0.08 | uM | 15392.211 | 0.8756 | 0.9124 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 0.4 | uM | 15392.211 | 0.8454 | 0.8899 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 2 | uM | 15392.211 | 0.9080 | 0.9360 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 10 | uM | 15392.211 | 0.6706 | 0.7480 | 2.9667 | |||
| MCF 10A | NM | Basal B | Ribavirin | 50 | uM | 15392.211 | 0.5396 | 0.6244 | 2.9667 | |||
| MCF 10F | NM | - | Ribavirin | 0.000128 | uM | 15393.211 | 0.9860 | 0.9829 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 0.00064 | uM | 15393.211 | 0.9769 | 0.9718 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 0.0032 | uM | 15393.211 | 0.9496 | 0.9381 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 0.016 | uM | 15393.211 | 0.9287 | 0.9121 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 0.08 | uM | 15393.211 | 1.0104 | 1.0126 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 0.4 | uM | 15393.211 | 1.1240 | 1.1473 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 2 | uM | 15393.211 | 1.1836 | 1.2158 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 10 | uM | 15393.211 | 1.0548 | 1.0659 | 1.6449 | |||
| MCF 10F | NM | - | Ribavirin | 50 | uM | 15393.211 | 0.8682 | 0.8354 | 1.6449 | |||
| MCF12A | NM | Basal B | Ribavirin | 0.000128 | uM | 15354.211 | 0.9377 | 0.9377 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 0.00064 | uM | 15354.211 | 0.9173 | 0.9168 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 0.0032 | uM | 15354.211 | 0.9101 | 0.9094 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 0.016 | uM | 15354.211 | 0.9328 | 0.9327 | 2.0320 | |||
| MCF12A | NM | Basal B | Ribavirin | 0.08 | uM | 15354.211 | 0.9400 | 0.9400 | 2.0320 |