Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | QNZ | NFkB | NFKB | 6.67 | uM | 7553.096 | 0.6595 | 0.3885 | 1.1407 | |
| ZR-75-1 | HR+ | Luminal | QNZ | NFkB | NFKB | 33.3 | uM | 7553.096 | 0.5938 | 0.2664 | 1.1407 | |
| 21MT-1 | HER2amp | - | Ribavirin | 0.000128 | uM | 15382.211 | 0.9843 | 0.9732 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 0.00064 | uM | 15382.211 | 0.9190 | 0.8608 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 0.0032 | uM | 15382.211 | 0.9456 | 0.9067 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 0.016 | uM | 15382.211 | 0.9381 | 0.8938 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 0.08 | uM | 15382.211 | 0.9581 | 0.9283 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 0.4 | uM | 15382.211 | 1.0123 | 1.0210 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 2 | uM | 15382.211 | 1.0208 | 1.0354 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 10 | uM | 15382.211 | 1.0377 | 1.0642 | 1.1714 | |||
| 21MT-1 | HER2amp | - | Ribavirin | 50 | uM | 15382.211 | 0.9815 | 0.9683 | 1.1714 | |||
| 21NT | HER2amp | - | Ribavirin | 0.000128 | uM | 15383.211 | 0.9501 | 0.9033 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.00064 | uM | 15383.211 | 0.9100 | 0.8256 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.0032 | uM | 15383.211 | 0.9196 | 0.8443 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.016 | uM | 15383.211 | 0.9351 | 0.8743 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.08 | uM | 15383.211 | 1.0137 | 1.0265 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 0.4 | uM | 15383.211 | 1.0060 | 1.0116 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 2 | uM | 15383.211 | 1.0639 | 1.1234 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 10 | uM | 15383.211 | 1.0191 | 1.0369 | 1.0341 | |||
| 21NT | HER2amp | - | Ribavirin | 50 | uM | 15383.211 | 1.0038 | 1.0074 | 1.0341 | |||
| AU565 | HER2amp | Luminal | Ribavirin | 0.000128 | uM | 15384.211 | 1.0049 | 1.0075 | 1.3162 | |||
| AU565 | HER2amp | Luminal | Ribavirin | 0.00064 | uM | 15384.211 | 0.9859 | 0.9786 | 1.3162 | |||
| AU565 | HER2amp | Luminal | Ribavirin | 0.0032 | uM | 15384.211 | 0.9801 | 0.9696 | 1.3162 | |||
| AU565 | HER2amp | Luminal | Ribavirin | 0.016 | uM | 15384.211 | 1.0084 | 1.0127 | 1.3162 | |||
| AU565 | HER2amp | Luminal | Ribavirin | 0.08 | uM | 15384.211 | 1.0948 | 1.1424 | 1.3162 |