Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 7546.067 | 1.0607 | 1.1433 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 7546.067 | 1.0367 | 1.0864 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 7546.067 | 1.0061 | 1.0144 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 7546.067 | 1.0411 | 1.0969 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 0.267 | uM | 7546.067 | 1.0517 | 1.1220 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 1.33 | uM | 7546.067 | 0.9777 | 0.9478 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 6.67 | uM | 7546.067 | 1.0788 | 1.1863 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 33.3 | uM | 7546.067 | 0.9356 | 0.8496 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Purvalanol A | CDK1 | CDK | 167 | uM | 7546.067 | 0.8926 | 0.7500 | 0.8509 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 7552.067 | 1.0068 | 1.0132 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 7552.067 | 0.9953 | 0.9909 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 7552.067 | 0.9774 | 0.9558 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 7552.067 | 0.9856 | 0.9718 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.267 | uM | 7552.067 | 0.9924 | 0.9851 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 1.33 | uM | 7552.067 | 0.9584 | 0.9186 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 6.67 | uM | 7552.067 | 1.0193 | 1.0378 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 33.3 | uM | 7552.067 | 0.7254 | 0.4611 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 167 | uM | 7552.067 | 0.7512 | 0.5118 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 7553.067 | 1.0503 | 1.0887 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 7553.067 | 0.9834 | 0.9706 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 7553.067 | 1.0077 | 1.0136 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 7553.067 | 0.9772 | 0.9596 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 0.267 | uM | 7553.067 | 1.0119 | 1.0210 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 1.33 | uM | 7553.067 | 0.9906 | 0.9834 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Purvalanol A | CDK1 | CDK | 6.67 | uM | 7553.067 | 1.0296 | 1.0523 | 1.1302 |