Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MB 157	Unknown	Unknown	Sigma A6730	AKT	AKT	13.3	uM	12580.165	0.5214	0.5046	2.2883
MB 157	Unknown	Unknown	Sigma A6730	AKT	AKT	66.7	uM	12580.165	0.0149	-0.6815	2.2883
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	0.000171	uM	11056.158	0.9960	0.9971	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	0.000853	uM	11056.158	1.0905	1.0644	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	0.00427	uM	11056.158	1.0089	1.0065	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	0.0213	uM	11056.158	1.0132	1.0096	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	0.107	uM	11056.158	0.9917	0.9939	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	0.533	uM	11056.158	0.8723	0.9026	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	2.67	uM	11056.158	0.7157	0.7698	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	13.3	uM	11056.158	0.2854	0.2647	2.7355
MCF 10A	NM	Basal B	Sigma A6730	AKT	AKT	66.7	uM	11056.158	0.0069	-0.6765	2.7355
MCF 10F	NM	-	Sigma A6730	AKT	AKT	0.000171	uM	12254.165	0.9679	0.9620	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	0.000853	uM	12254.165	0.9955	0.9947	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	0.00427	uM	12254.165	0.9926	0.9913	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	0.0213	uM	12254.165	0.9704	0.9649	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	0.107	uM	12254.165	0.9179	0.9016	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	0.533	uM	12254.165	0.8861	0.8625	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	2.67	uM	12254.165	0.7096	0.6341	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	13.3	uM	12254.165	0.3847	0.1394	1.6980
MCF 10F	NM	-	Sigma A6730	AKT	AKT	66.7	uM	12254.165	0.0092	-0.8736	1.6980
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.000171	uM	10817.153	0.9450	0.9335	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.000853	uM	10817.153	0.9829	0.9795	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.00427	uM	10817.153	0.9470	0.9359	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.0213	uM	10817.153	0.9595	0.9512	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.107	uM	10817.153	0.9821	0.9785	1.6726

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)