Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000171 | uM | 10473.141 | 0.8673 | 0.7895 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000853 | uM | 10473.141 | 0.8930 | 0.8308 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10473.141 | 0.9192 | 0.8727 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10473.141 | 0.9323 | 0.8934 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 10473.141 | 0.9599 | 0.9370 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 10473.141 | 0.9358 | 0.8989 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 10473.141 | 0.8609 | 0.7792 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 13.3 | uM | 10473.141 | 0.4666 | 0.1027 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 66.7 | uM | 10473.141 | 0.0931 | -0.6868 | 1.2804 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000171 | uM | 10755.153 | 0.9533 | 0.8760 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000853 | uM | 10755.153 | 0.9045 | 0.7485 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10755.153 | 0.9616 | 0.8979 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10755.153 | 0.9979 | 0.9943 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 10755.153 | 1.0530 | 1.1431 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 10755.153 | 0.9664 | 0.9106 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 10755.153 | 1.0143 | 1.0384 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 13.3 | uM | 10755.153 | 0.5891 | -0.0150 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 66.7 | uM | 10755.153 | 0.3181 | -0.5684 | 0.7471 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12070.158 | 0.9547 | 0.9193 | 1.1252 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12070.158 | 1.0500 | 1.0886 | 1.1252 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12070.158 | 0.8871 | 0.7980 | 1.1252 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12070.158 | 0.9602 | 0.9290 | 1.1252 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 12070.158 | 1.0004 | 1.0007 | 1.1252 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 12070.158 | 0.9262 | 0.8683 | 1.1252 | |
CAMA-1 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 12070.158 | 0.6919 | 0.4417 | 1.1252 |