Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5896.067 | 0.0103 | -0.9139 | 1.4536 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5896.067 | 0.0036 | -0.9586 | 1.4536 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5897.067 | 0.9703 | 0.9500 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5897.067 | 1.0337 | 1.0565 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5897.067 | 0.9779 | 0.9629 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5897.067 | 1.0019 | 1.0032 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5897.067 | 1.0076 | 1.0128 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5897.067 | 0.9640 | 0.9394 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5897.067 | 0.7592 | 0.5869 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5897.067 | 0.0105 | -0.9565 | 1.1908 | |
| 184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5897.067 | 0.0078 | -0.9660 | 1.1908 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5898.067 | 0.9710 | 0.9118 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5898.067 | 0.9569 | 0.8694 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5898.067 | 0.9864 | 0.9586 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5898.067 | 0.8067 | 0.4395 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5898.067 | 1.0098 | 1.0301 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5898.067 | 0.9845 | 0.9528 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5898.067 | 0.7120 | 0.1888 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5898.067 | 0.0086 | -0.9986 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5898.067 | 0.0088 | -0.9986 | 0.6532 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5899.067 | 0.9347 | 0.8681 | 0.9897 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5899.067 | 0.9363 | 0.8713 | 0.9897 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5899.067 | 0.9910 | 0.9819 | 0.9897 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5899.067 | 0.9425 | 0.8838 | 0.9897 | |
| 600MPE | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5899.067 | 0.9592 | 0.9176 | 0.9897 |