Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5894.067 | 0.9820 | 0.9769 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5894.067 | 1.0917 | 1.1154 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5894.067 | 1.0322 | 1.0409 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5894.067 | 1.0908 | 1.1143 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5894.067 | 1.0921 | 1.1158 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5894.067 | 0.8601 | 0.8163 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5894.067 | 0.4589 | 0.2157 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5894.067 | 0.0087 | -0.9035 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5894.067 | 0.0040 | -0.9413 | 1.5647 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5895.067 | 1.0183 | 1.0260 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5895.067 | 1.0772 | 1.1087 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5895.067 | 1.0273 | 1.0387 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5895.067 | 1.0675 | 1.0952 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5895.067 | 1.0807 | 1.1135 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5895.067 | 0.9996 | 0.9995 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5895.067 | 0.5280 | 0.2696 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5895.067 | 0.0235 | -0.8614 | 1.4053 | |
184A1 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5895.067 | 0.0121 | -0.9135 | 1.4053 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5896.067 | 1.0275 | 1.0377 | 1.4536 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5896.067 | 1.0064 | 1.0088 | 1.4536 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5896.067 | 1.0153 | 1.0210 | 1.4536 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5896.067 | 1.0509 | 1.0695 | 1.4536 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5896.067 | 0.9964 | 0.9950 | 1.4536 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5896.067 | 0.8858 | 0.8400 | 1.4536 | |
184B5 | NM | Basal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5896.067 | 0.4849 | 0.2156 | 1.4536 |