Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.00427
uM
10696.153
0.9681 0.8852 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.0213
uM
10696.153
1.0117 1.0430 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.107
uM
10696.153
1.0169 1.0622 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.533
uM
10696.153
0.9188 0.7137 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
2.67
uM
10696.153
0.7327 0.1344 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
13.3
uM
10696.153
0.5598 -0.3056 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
66.7
uM
10696.153
0.3830 -0.6524 0.5484
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.000171
uM
11855.158
0.9331 0.8102 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.000853
uM
11855.158
0.9031 0.7269 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.00427
uM
11855.158
0.9495 0.8562 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.0213
uM
11855.158
0.8521 0.5882 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.107
uM
11855.158
0.8312 0.5322 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
0.533
uM
11855.158
0.8141 0.4872 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
2.67
uM
11855.158
0.6612 0.1020 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
13.3
uM
11855.158
0.5070 -0.2484 0.6941
BT-483
HR+
Luminal
Sigma A6730
AKT
AKT
66.7
uM
11855.158
0.3056 -0.6376 0.6941
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
0.000171
uM
12305.165
0.8971 0.9212 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
0.000853
uM
12305.165
0.9230 0.9416 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
0.00427
uM
12305.165
0.9195 0.9388 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
0.0213
uM
12305.165
0.9044 0.9270 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
0.107
uM
12305.165
0.8683 0.8982 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
0.533
uM
12305.165
0.9355 0.9513 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
2.67
uM
12305.165
0.7920 0.8346 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
13.3
uM
12305.165
0.4249 0.4570 2.7020
BT-549
TNBC
Basal B
Sigma A6730
AKT
AKT
66.7
uM
12305.165
0.0005 -0.8811 2.7020