Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10696.153 | 0.9681 | 0.8852 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10696.153 | 1.0117 | 1.0430 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 10696.153 | 1.0169 | 1.0622 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 10696.153 | 0.9188 | 0.7137 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 10696.153 | 0.7327 | 0.1344 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 13.3 | uM | 10696.153 | 0.5598 | -0.3056 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 66.7 | uM | 10696.153 | 0.3830 | -0.6524 | 0.5484 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000171 | uM | 11855.158 | 0.9331 | 0.8102 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000853 | uM | 11855.158 | 0.9031 | 0.7269 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 11855.158 | 0.9495 | 0.8562 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 11855.158 | 0.8521 | 0.5882 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 11855.158 | 0.8312 | 0.5322 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 11855.158 | 0.8141 | 0.4872 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 11855.158 | 0.6612 | 0.1020 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 13.3 | uM | 11855.158 | 0.5070 | -0.2484 | 0.6941 | |
BT-483 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 66.7 | uM | 11855.158 | 0.3056 | -0.6376 | 0.6941 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12305.165 | 0.8971 | 0.9212 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12305.165 | 0.9230 | 0.9416 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12305.165 | 0.9195 | 0.9388 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12305.165 | 0.9044 | 0.9270 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.107 | uM | 12305.165 | 0.8683 | 0.8982 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.533 | uM | 12305.165 | 0.9355 | 0.9513 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 2.67 | uM | 12305.165 | 0.7920 | 0.8346 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 13.3 | uM | 12305.165 | 0.4249 | 0.4570 | 2.7020 | |
BT-549 | TNBC | Basal B | Sigma A6730 | AKT | AKT | 66.7 | uM | 12305.165 | 0.0005 | -0.8811 | 2.7020 |