Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000171 | uM | 10816.153 | 1.0231 | 1.0602 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000853 | uM | 10816.153 | 1.1090 | 1.2874 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10816.153 | 1.0539 | 1.1411 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10816.153 | 0.8541 | 0.6297 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 10816.153 | 0.9040 | 0.7544 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 10816.153 | 0.9903 | 0.9749 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 10816.153 | 0.6910 | 0.2379 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 13.3 | uM | 10816.153 | 0.2302 | -0.7029 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 66.7 | uM | 10816.153 | 0.0088 | -0.9957 | 0.7704 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12319.165 | 0.7757 | 0.5138 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12319.165 | 0.9013 | 0.7846 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12319.165 | 0.9336 | 0.8548 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12319.165 | 0.8035 | 0.5733 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.107 | uM | 12319.165 | 1.0669 | 1.1473 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 0.533 | uM | 12319.165 | 0.8417 | 0.6554 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 2.67 | uM | 12319.165 | 0.5985 | 0.1391 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 13.3 | uM | 12319.165 | 0.1735 | -0.7072 | 0.9117 | |
| LY2 | HR+ | Luminal | Sigma A6730 | AKT | AKT | 66.7 | uM | 12319.165 | 0.0102 | -0.9869 | 0.9117 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12580.165 | 1.0213 | 1.0185 | 2.2883 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12580.165 | 1.0231 | 1.0201 | 2.2883 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12580.165 | 0.9424 | 0.9488 | 2.2883 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12580.165 | 0.7558 | 0.7697 | 2.2883 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 0.107 | uM | 12580.165 | 0.9790 | 0.9815 | 2.2883 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 0.533 | uM | 12580.165 | 1.0181 | 1.0158 | 2.2883 | |
| MB 157 | Unknown | Unknown | Sigma A6730 | AKT | AKT | 2.67 | uM | 12580.165 | 1.0295 | 1.0256 | 2.2883 |