Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10873.153 | 0.9369 | 0.9051 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10873.153 | 0.9303 | 0.8950 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.107 | uM | 10873.153 | 0.9763 | 0.9646 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.533 | uM | 10873.153 | 0.8706 | 0.8034 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 2.67 | uM | 10873.153 | 0.5451 | 0.2715 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 13.3 | uM | 10873.153 | 0.2188 | -0.3567 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 66.7 | uM | 10873.153 | 0.0554 | -0.7692 | 1.3397 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.000171 | uM | 12400.165 | 0.9675 | 0.9500 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.000853 | uM | 12400.165 | 0.9581 | 0.9354 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.00427 | uM | 12400.165 | 0.9582 | 0.9357 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.0213 | uM | 12400.165 | 0.9629 | 0.9429 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.107 | uM | 12400.165 | 0.9920 | 0.9877 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 0.533 | uM | 12400.165 | 0.9233 | 0.8814 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 2.67 | uM | 12400.165 | 0.6101 | 0.3698 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 13.3 | uM | 12400.165 | 0.2945 | -0.2158 | 1.3057 | |
| HCC70 | TNBC | Basal A | Sigma A6730 | AKT | AKT | 66.7 | uM | 12400.165 | 0.0374 | -0.8387 | 1.3057 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000171 | uM | 10694.153 | 0.9806 | 0.9830 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000853 | uM | 10694.153 | 0.9276 | 0.9355 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10694.153 | 0.9813 | 0.9836 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10694.153 | 1.0266 | 1.0231 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.107 | uM | 10694.153 | 1.0041 | 1.0036 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.533 | uM | 10694.153 | 1.0101 | 1.0088 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 2.67 | uM | 10694.153 | 0.9124 | 0.9216 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 13.3 | uM | 10694.153 | 0.5890 | 0.5879 | 2.2940 | |
| Hs 578T | TNBC | Basal B | Sigma A6730 | AKT | AKT | 66.7 | uM | 10694.153 | 0.0085 | -0.7493 | 2.2940 |