Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7440.067 | 0.9862 | 0.9226 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7440.067 | 0.9983 | 0.9905 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7440.067 | 1.0043 | 1.0245 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7440.067 | 1.0081 | 1.0464 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7440.067 | 1.0591 | 1.3544 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7440.067 | 1.0404 | 1.2385 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7440.067 | 1.0353 | 1.2074 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7440.067 | 0.0224 | -1.0000 | 0.3519 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7440.067 | 0.0090 | -1.0000 | 0.3519 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7441.067 | 0.9848 | 0.9630 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7441.067 | 1.0100 | 1.0242 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7441.067 | 0.9624 | 0.9090 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7441.067 | 0.9958 | 0.9899 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7441.067 | 0.9772 | 0.9448 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7441.067 | 0.8517 | 0.6458 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7441.067 | 0.6884 | 0.2708 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7441.067 | 0.0103 | -0.9923 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7441.067 | 0.0042 | -0.9974 | 0.8233 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7442.067 | 0.9393 | 0.8673 | 0.9126 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7442.067 | 0.9269 | 0.8403 | 0.9126 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7442.067 | 0.9584 | 0.9089 | 0.9126 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7442.067 | 0.9862 | 0.9698 | 0.9126 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7442.067 | 0.9432 | 0.8759 | 0.9126 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7442.067 | 0.9492 | 0.8889 | 0.9126 | |
| HCC1428 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7442.067 | 0.6741 | 0.2982 | 0.9126 |