Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 0.00853 | uM | 10520.136 | 1.0646 | 1.0313 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 0.0427 | uM | 10520.136 | 1.0051 | 1.0025 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 0.213 | uM | 10520.136 | 0.9684 | 0.9841 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 1.07 | uM | 10520.136 | 0.9024 | 0.9497 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 5.33 | uM | 10520.136 | 1.1702 | 1.0795 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 26.7 | uM | 10520.136 | 0.9538 | 0.9767 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Sulindac sulfide | COX1/2 | COX | 133 | uM | 10520.136 | 0.9799 | 0.9899 | 4.0331 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 0.000341 | uM | 10579.136 | 1.0219 | 1.0641 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 0.00171 | uM | 10579.136 | 1.0647 | 1.1908 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 0.00853 | uM | 10579.136 | 1.0053 | 1.0155 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 0.0427 | uM | 10579.136 | 1.0771 | 1.2280 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 0.213 | uM | 10579.136 | 1.0590 | 1.1738 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 1.07 | uM | 10579.136 | 0.9932 | 0.9804 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 5.33 | uM | 10579.136 | 1.0324 | 1.0948 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 26.7 | uM | 10579.136 | 1.1444 | 1.4335 | 0.6876 | |
| SUM225CWN | HER2amp | Basal A | Sulindac sulfide | COX1/2 | COX | 133 | uM | 10579.136 | 1.0182 | 1.0531 | 0.6876 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 0.000341 | uM | 10580.136 | 0.9261 | 0.7980 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 0.00171 | uM | 10580.136 | 0.8702 | 0.6489 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 0.00853 | uM | 10580.136 | 0.9614 | 0.8936 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 0.0427 | uM | 10580.136 | 0.9923 | 0.9786 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 0.213 | uM | 10580.136 | 0.9691 | 0.9148 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 1.07 | uM | 10580.136 | 0.9303 | 0.8091 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 5.33 | uM | 10580.136 | 0.8880 | 0.6959 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 26.7 | uM | 10580.136 | 1.0008 | 1.0022 | 0.7205 | |
| UACC-812 | HER2amp | Luminal | Sulindac sulfide | COX1/2 | COX | 133 | uM | 10580.136 | 0.9681 | 0.9119 | 0.7205 |