Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10644.14 | 0.0078 | -1.0000 | 0.4302 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10644.14 | 0.0044 | -1.0000 | 0.4302 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10874.152 | 1.0250 | 1.0651 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10874.152 | 1.0476 | 1.1244 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10874.152 | 1.0292 | 1.0760 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10874.152 | 1.0492 | 1.1285 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10874.152 | 1.0120 | 1.0313 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10874.152 | 0.8186 | 0.5424 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10874.152 | 0.0658 | -0.9415 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10874.152 | 0.0167 | -0.9901 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10874.152 | 0.0173 | -0.9896 | 0.7706 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12220.159 | 0.9554 | 0.8182 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12220.159 | 0.9609 | 0.8401 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12220.159 | 1.0000 | 1.0000 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12220.159 | 1.0334 | 1.1422 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12220.159 | 1.0078 | 1.0329 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12220.159 | 0.7466 | 0.0865 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 1.33 | uM | 12220.159 | 0.1742 | -0.9480 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 6.67 | uM | 12220.159 | 0.0683 | -0.9926 | 0.4788 | |
| MX1 | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 33.3 | uM | 12220.159 | 0.0495 | -0.9963 | 0.4788 | |
| SK-BR-3 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 11851.159 | 0.9942 | 0.9908 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 11851.159 | 0.9385 | 0.9015 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 11851.159 | 1.0460 | 1.0728 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 11851.159 | 0.8661 | 0.7841 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 11851.159 | 0.9693 | 0.9510 | 1.2582 |