Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7435.067 | 1.0184 | 1.0479 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7435.067 | 1.0307 | 1.0803 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7435.067 | 1.0373 | 1.0975 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7435.067 | 0.9272 | 0.8128 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7435.067 | 0.5459 | -0.0897 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7435.067 | 0.0005 | -0.9999 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7435.067 | 1.1452 | 1.3857 | 0.7691 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7436.067 | 0.9615 | 0.9398 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7436.067 | 1.0083 | 1.0130 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7436.067 | 0.9708 | 0.9543 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7436.067 | 1.0005 | 1.0007 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7436.067 | 1.0242 | 1.0376 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7436.067 | 0.9781 | 0.9658 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7436.067 | 0.6537 | 0.4361 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7436.067 | 0.0112 | -0.9396 | 1.2834 | |
| HCC1395 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7436.067 | 0.0016 | -0.9870 | 1.2834 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7437.067 | 1.0006 | 1.0031 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7437.067 | 1.0435 | 1.2226 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7437.067 | 1.0457 | 1.2342 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7437.067 | 1.0601 | 1.3108 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7437.067 | 1.0676 | 1.3515 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7437.067 | 1.0249 | 1.1255 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7437.067 | 1.0288 | 1.1458 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7437.067 | 0.0697 | -0.9973 | 0.4038 | |
| HCC1419 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7437.067 | 1.1593 | 1.8842 | 0.4038 |