Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.533	uM	10817.153	0.8660	0.8351	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	2.67	uM	10817.153	0.8165	0.7716	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	13.3	uM	10817.153	0.5763	0.4385	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	66.7	uM	10817.153	0.1559	-0.3416	1.6726
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.000171	uM	12365.165	1.0207	1.0215	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.000853	uM	12365.165	0.9667	0.9649	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.00427	uM	12365.165	1.0141	1.0147	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.0213	uM	12365.165	1.0400	1.0415	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.107	uM	12365.165	0.9979	0.9978	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	0.533	uM	12365.165	1.0352	1.0365	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	2.67	uM	12365.165	0.8600	0.8483	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	13.3	uM	12365.165	0.6046	0.5371	1.9114
MCF12A	NM	Basal B	Sigma A6730	AKT	AKT	66.7	uM	12365.165	0.0090	-0.8300	1.9114
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	10997.153	0.9576	0.9212	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	10997.153	0.9388	0.8860	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	10997.153	0.9310	0.8715	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	10997.153	0.9305	0.8707	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	0.107	uM	10997.153	0.9410	0.8902	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	0.533	uM	10997.153	0.8819	0.7797	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	2.67	uM	10997.153	0.6385	0.3186	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	13.3	uM	10997.153	0.1839	-0.5848	1.0771
MCF7	HR+	Luminal	Sigma A6730	AKT	AKT	66.7	uM	10997.153	0.0125	-0.9658	1.0771
MDA-MB-134-VI	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	10519.141	0.9466	0.8974	1.0417
MDA-MB-134-VI	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	10519.141	0.9741	0.9502	1.0417
MDA-MB-134-VI	HR+	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	10519.141	0.9871	0.9753	1.0417

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)