Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-134-VI	HR+	Luminal	Ro 32-0432	PKC	PKC	0.267	uM	10519.142	0.9259	0.8353	0.8963
MDA-MB-134-VI	HR+	Luminal	Ro 32-0432	PKC	PKC	1.33	uM	10519.142	0.9293	0.8429	0.8963
MDA-MB-134-VI	HR+	Luminal	Ro 32-0432	PKC	PKC	6.67	uM	10519.142	0.9796	0.9545	0.8963
MDA-MB-134-VI	HR+	Luminal	Ro 32-0432	PKC	PKC	33.3	uM	10519.142	1.0034	1.0077	0.8963
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	0.0000853	uM	10642.142	0.9980	0.9921	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	0.000427	uM	10642.142	0.9768	0.9083	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	0.00213	uM	10642.142	0.9836	0.9351	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	0.0107	uM	10642.142	1.0282	1.1143	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	0.0533	uM	10642.142	1.0379	1.1543	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	0.267	uM	10642.142	0.9689	0.8778	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	1.33	uM	10642.142	0.9765	0.9072	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	6.67	uM	10642.142	0.9702	0.8827	0.5006
MDA-MB-175-VII	HR+	Luminal	Ro 32-0432	PKC	PKC	33.3	uM	10642.142	1.0288	1.1166	0.5006
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	0.0000853	uM	10643.142	1.0310	1.1218	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	0.000427	uM	10643.142	1.0253	1.0990	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	0.00213	uM	10643.142	1.0032	1.0123	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	0.0107	uM	10643.142	1.0074	1.0289	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	0.0533	uM	10643.142	1.0305	1.1198	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	0.267	uM	10643.142	0.9834	0.9362	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	1.33	uM	10643.142	1.0256	1.1004	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	6.67	uM	10643.142	1.0331	1.1300	0.5166
MDA-MB-361	HER2amp	Luminal	Ro 32-0432	PKC	PKC	33.3	uM	10643.142	1.0153	1.0595	0.5166
MX1	Unknown	Unknown	Ro 32-0432	PKC	PKC	0.0000853	uM	10644.142	1.0244	1.0954	0.5163
MX1	Unknown	Unknown	Ro 32-0432	PKC	PKC	0.000427	uM	10644.142	0.9224	0.7103	0.5163
MX1	Unknown	Unknown	Ro 32-0432	PKC	PKC	0.00213	uM	10644.142	0.9871	0.9504	0.5163

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)