Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC202 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7841.068 | 0.6310 | -0.0217 | 0.6440 | |
HCC202 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 7841.068 | 0.5568 | -0.1944 | 0.6440 | |
HCC202 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 7841.068 | 0.5730 | -0.1577 | 0.6440 | |
HCC202 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 7841.068 | 0.5621 | -0.1824 | 0.6440 | |
HCC202 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 7841.068 | 0.3851 | -0.5456 | 0.6440 | |
HCC202 | HER2amp | Luminal | Sirolimus | MTOR | MTOR | 167 | uM | 7841.068 | 0.0089 | -0.9987 | 0.6440 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7463.068 | 0.8261 | 0.4456 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7463.068 | 0.7864 | 0.3297 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7463.068 | 0.7397 | 0.1983 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7463.068 | 0.7026 | 0.0982 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 7463.068 | 0.6992 | 0.0891 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 7463.068 | 0.7164 | 0.1349 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 7463.068 | 0.7349 | 0.1852 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 7463.068 | 0.6390 | -0.0655 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 167 | uM | 7463.068 | 0.6582 | -0.0172 | 0.5887 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 7464.069 | 0.9757 | 0.9256 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7464.069 | 0.9780 | 0.9328 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7464.069 | 0.7614 | 0.3145 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7464.069 | 0.6248 | -0.0305 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7464.069 | 0.6678 | 0.0740 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 7464.069 | 0.6567 | 0.0468 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 7464.069 | 0.6726 | 0.0861 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 7464.069 | 0.6451 | 0.0184 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 7464.069 | 0.5767 | -0.1430 | 0.6495 | |
HCC2185 | TNBC | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7845.068 | 0.9388 | 0.6976 | 0.3849 |