Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
HCC1954	HER2amp	Basal A	Sirolimus	MTOR	MTOR	1.33	uM	7836.068	0.4794	0.2746	1.6317
HCC1954	HER2amp	Basal A	Sirolimus	MTOR	MTOR	6.67	uM	7836.068	0.5013	0.3100	1.6317
HCC1954	HER2amp	Basal A	Sirolimus	MTOR	MTOR	33.3	uM	7836.068	0.3853	0.1147	1.6317
HCC1954	HER2amp	Basal A	Sirolimus	MTOR	MTOR	167	uM	7836.068	0.2213	-0.2064	1.6317
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0000853	uM	7458.069	1.0229	1.1044	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.000427	uM	7458.069	1.0559	1.2605	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.00213	uM	7458.069	0.9278	0.6896	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0107	uM	7458.069	0.8109	0.2480	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0533	uM	7458.069	0.6873	-0.1398	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.267	uM	7458.069	0.6722	-0.1817	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	1.33	uM	7458.069	0.6678	-0.1937	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	6.67	uM	7458.069	0.6079	-0.3473	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	33.3	uM	7458.069	0.6423	-0.2614	0.4444
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.000427	uM	7840.068	0.9536	0.7618	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.00213	uM	7840.068	1.0489	1.2714	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0107	uM	7840.068	0.8557	0.3197	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0533	uM	7840.068	0.6665	-0.3223	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.267	uM	7840.068	0.7107	-0.1959	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	1.33	uM	7840.068	0.6636	-0.3301	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	6.67	uM	7840.068	0.7468	-0.0821	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	33.3	uM	7840.068	0.6208	-0.4394	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	167	uM	7840.068	0.6516	-0.3621	0.3749
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.000427	uM	7841.068	0.8867	0.6592	0.6440
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.00213	uM	7841.068	0.8522	0.5602	0.6440
HCC202	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0107	uM	7841.068	0.6881	0.1193	0.6440

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)