Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7485.096 | 1.0178 | 1.0098 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7485.096 | 0.9429 | 0.9678 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7485.096 | 0.9236 | 0.9566 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7485.096 | 0.8443 | 0.9088 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7485.096 | 0.7964 | 0.8783 | 3.6265 | ||
| MCF 10A | NM | Basal B | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7485.096 | 0.7748 | 0.8642 | 3.6265 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7490.096 | 1.0112 | 1.0086 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7490.096 | 0.9377 | 0.9507 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7490.096 | 0.9934 | 0.9949 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7490.096 | 1.0135 | 1.0105 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7490.096 | 0.9702 | 0.9767 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7490.096 | 0.9681 | 0.9750 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7490.096 | 0.9869 | 0.9898 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7490.096 | 0.8662 | 0.8916 | 2.5767 | ||
| MCF12A | NM | Basal B | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7490.096 | 0.8531 | 0.8804 | 2.5767 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7493.096 | 0.9833 | 0.9713 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 7493.096 | 0.9573 | 0.9267 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 7493.096 | 1.0089 | 1.0153 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 7493.096 | 0.9777 | 0.9618 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 7493.096 | 0.9965 | 0.9940 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 7493.096 | 0.9421 | 0.9004 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 7493.096 | 0.9312 | 0.8815 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 7493.096 | 0.9044 | 0.8351 | 1.1669 | ||
| MCF7 | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 7493.096 | 0.8160 | 0.6802 | 1.1669 | ||
| MDA-MB-157 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 7496.096 | 0.9165 | 0.8444 | 1.0771 |