Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10518.142 | 0.9977 | 0.9965 | 1.2869 | |
HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10518.142 | 1.0083 | 1.0128 | 1.2869 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10577.142 | 1.0008 | 1.0016 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10577.142 | 0.8930 | 0.7973 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10577.142 | 0.9415 | 0.8894 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10577.142 | 0.9279 | 0.8634 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10577.142 | 0.9333 | 0.8737 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10577.142 | 0.9343 | 0.8756 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10577.142 | 0.9520 | 0.9092 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10577.142 | 0.9594 | 0.9232 | 1.0584 | |
HCC3153 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10577.142 | 0.9295 | 0.8665 | 1.0584 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10578.142 | 0.9773 | 0.9748 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10578.142 | 0.9294 | 0.9208 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10578.142 | 0.8927 | 0.8786 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10578.142 | 0.9159 | 0.9053 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10578.142 | 0.9740 | 0.9711 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10578.142 | 0.8876 | 0.8725 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10578.142 | 1.0180 | 1.0198 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10578.142 | 0.9605 | 0.9560 | 1.8112 | |
HCC38 | TNBC | Basal B | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10578.142 | 0.9899 | 0.9888 | 1.8112 | |
MDA-MB-134-VI | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10519.142 | 0.9863 | 0.9694 | 0.8963 | |
MDA-MB-134-VI | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10519.142 | 0.9020 | 0.7826 | 0.8963 | |
MDA-MB-134-VI | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10519.142 | 0.9517 | 0.8925 | 0.8963 | |
MDA-MB-134-VI | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10519.142 | 0.9795 | 0.9543 | 0.8963 | |
MDA-MB-134-VI | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10519.142 | 0.9722 | 0.9381 | 0.8963 |