Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10581.142 | 1.0689 | 1.1763 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10581.142 | 0.9204 | 0.8002 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10581.142 | 0.9994 | 0.9986 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10581.142 | 1.0449 | 1.1146 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10581.142 | 1.0093 | 1.0235 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10581.142 | 0.9865 | 0.9658 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10581.142 | 1.0536 | 1.1369 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10581.142 | 1.0177 | 1.0451 | 0.7885 | |
| BT-20 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10581.142 | 1.0667 | 1.1706 | 0.7885 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10473.142 | 1.0347 | 1.0641 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10473.142 | 0.9519 | 0.9108 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10473.142 | 1.0109 | 1.0202 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10473.142 | 1.0259 | 1.0479 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10473.142 | 1.0544 | 1.1004 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10473.142 | 1.0196 | 1.0363 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10473.142 | 0.9908 | 0.9829 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 6.67 | uM | 10473.142 | 1.0301 | 1.0555 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Ro 32-0432 | PKC | PKC | 33.3 | uM | 10473.142 | 1.0205 | 1.0380 | 1.0815 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0000853 | uM | 10518.142 | 1.0243 | 1.0376 | 1.2869 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.000427 | uM | 10518.142 | 0.9480 | 0.9187 | 1.2869 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.00213 | uM | 10518.142 | 1.0040 | 1.0062 | 1.2869 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0107 | uM | 10518.142 | 0.9749 | 0.9609 | 1.2869 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.0533 | uM | 10518.142 | 1.0510 | 1.0788 | 1.2869 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 0.267 | uM | 10518.142 | 0.9972 | 0.9956 | 1.2869 | |
| HCC1187 | TNBC | Basal A | Ro 32-0432 | PKC | PKC | 1.33 | uM | 10518.142 | 0.9915 | 0.9867 | 1.2869 |