Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12523.168 | 0.9612 | 0.9143 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12523.168 | 0.9948 | 0.9885 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12523.168 | 1.0381 | 1.0846 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12523.168 | 1.0027 | 1.0060 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12523.168 | 1.0185 | 1.0409 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 167 | uM | 12523.168 | 1.0257 | 1.0569 | 0.9035 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12239.144 | 0.9626 | 0.9650 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12239.144 | 0.9859 | 0.9869 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12239.144 | 0.9806 | 0.9820 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12239.144 | 0.9927 | 0.9932 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12239.144 | 0.9599 | 0.9625 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12239.144 | 1.0235 | 1.0216 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 12239.144 | 0.9573 | 0.9600 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 12239.144 | 0.9156 | 0.9200 | 2.1598 | |
| HCC1806 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 12239.144 | 0.8268 | 0.8314 | 2.1598 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11849.144 | 1.0298 | 1.0420 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11849.144 | 1.0398 | 1.0560 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11849.144 | 0.9542 | 0.9347 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11849.144 | 1.0479 | 1.0673 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11849.144 | 0.9666 | 0.9524 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11849.144 | 1.0042 | 1.0059 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 11849.144 | 1.0276 | 1.0389 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 11849.144 | 0.9255 | 0.8934 | 1.4131 | |
| HCC1937 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 11849.144 | 0.7794 | 0.6766 | 1.4131 | |
| HCC1954 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11055.144 | 0.9051 | 0.8842 | 1.6716 |