Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 10381.065 | 1.0113 | 1.0182 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 10381.065 | 0.9936 | 0.9896 | 1.2390 | |
| SUM1315MO2 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 10381.065 | 0.9352 | 0.8948 | 1.2390 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7530.065 | 0.9307 | 0.9309 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7530.065 | 0.9278 | 0.9280 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7530.065 | 0.9224 | 0.9225 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7530.065 | 0.9686 | 0.9690 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7530.065 | 0.9935 | 0.9936 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7530.065 | 0.9465 | 0.9469 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7530.065 | 0.9681 | 0.9685 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7530.065 | 0.9422 | 0.9426 | 2.0424 | |
| SUM149PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7530.065 | 0.9456 | 0.9459 | 2.0424 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7531.065 | 1.0465 | 1.0266 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7531.065 | 1.0203 | 1.0117 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7531.065 | 1.1586 | 1.0873 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7531.065 | 1.0712 | 1.0403 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7531.065 | 1.0414 | 1.0237 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7531.065 | 1.0564 | 1.0321 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7531.065 | 1.1634 | 1.0898 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7531.065 | 1.1738 | 1.0952 | 3.4461 | |
| SUM159PT | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7531.065 | 1.0937 | 1.0527 | 3.4461 | |
| SUM185PE | TNBC | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7532.065 | 1.0913 | 1.2901 | 0.6453 | |
| SUM185PE | TNBC | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7532.065 | 1.0194 | 1.0603 | 0.6453 | |
| SUM185PE | TNBC | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7532.065 | 0.9857 | 0.9557 | 0.6453 | |
| SUM185PE | TNBC | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7532.065 | 1.0495 | 1.1555 | 0.6453 |