Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7485.065 | 1.0200 | 1.0111 | 3.5869 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 0.00485 | uM | 7486.065 | 1.1250 | 1.2154 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 0.0243 | uM | 7486.065 | 0.9683 | 0.9448 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 0.121 | uM | 7486.065 | 1.0076 | 1.0132 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 0.606 | uM | 7486.065 | 1.0686 | 1.1185 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 3.03 | uM | 7486.065 | 1.0549 | 1.0950 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 15.2 | uM | 7486.065 | 0.9716 | 0.9505 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 75.8 | uM | 7486.065 | 1.0496 | 1.0858 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 379 | uM | 7486.065 | 1.0370 | 1.0641 | 1.1517 | |
| MCF 10F | NM | - | PS-1145 | IKK | NFKB | 1890 | uM | 7486.065 | 1.1516 | 1.2607 | 1.1517 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7490.065 | 1.0577 | 1.0457 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7490.065 | 0.9851 | 0.9879 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7490.065 | 1.0076 | 1.0061 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7490.065 | 1.0792 | 1.0624 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7490.065 | 1.0560 | 1.0444 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7490.065 | 1.0197 | 1.0158 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7490.065 | 1.0080 | 1.0064 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7490.065 | 1.0357 | 1.0285 | 2.4816 | |
| MCF12A | NM | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7490.065 | 0.9042 | 0.9204 | 2.4816 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7492.065 | 0.9834 | 0.9792 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7492.065 | 1.0179 | 1.0222 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7492.065 | 0.9748 | 0.9685 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7492.065 | 0.9914 | 0.9893 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7492.065 | 0.9869 | 0.9837 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7492.065 | 0.9859 | 0.9824 | 1.6050 |