Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7453.065 | 1.0290 | 1.0347 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7453.065 | 0.9834 | 0.9800 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7453.065 | 0.9877 | 0.9852 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7453.065 | 0.9944 | 0.9932 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7453.065 | 0.9386 | 0.9253 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7453.065 | 0.9486 | 0.9377 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7453.065 | 1.0021 | 1.0025 | 1.6649 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7453.065 | 0.9124 | 0.8929 | 1.6649 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7454.065 | 1.0502 | 1.0956 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7454.065 | 0.8630 | 0.7380 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7454.065 | 0.9521 | 0.9086 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7454.065 | 0.9173 | 0.8420 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7454.065 | 0.9978 | 0.9957 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7454.065 | 0.8929 | 0.7953 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7454.065 | 1.0105 | 1.0200 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7454.065 | 0.9263 | 0.8592 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7454.065 | 0.8838 | 0.7779 | 1.0489 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7455.065 | 1.0384 | 1.0437 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7455.065 | 0.9831 | 0.9805 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7455.065 | 0.9332 | 0.9223 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7455.065 | 0.9788 | 0.9756 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7455.065 | 0.9850 | 0.9827 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7455.065 | 0.9799 | 0.9768 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7455.065 | 0.9843 | 0.9819 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7455.065 | 0.7971 | 0.7562 | 1.7441 |