Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7455.065 | 0.7523 | 0.6989 | 1.7441 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7456.065 | 1.0395 | 1.0393 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7456.065 | 0.9806 | 0.9804 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7456.065 | 0.9171 | 0.9149 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7456.065 | 0.9922 | 0.9921 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7456.065 | 1.0137 | 1.0137 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7456.065 | 0.7626 | 0.7453 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7456.065 | 0.9345 | 0.9331 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7456.065 | 0.7630 | 0.7458 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7456.065 | 0.6777 | 0.6448 | 1.9899 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7457.065 | 0.9452 | 0.9302 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7457.065 | 1.0797 | 1.0991 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7457.065 | 0.9454 | 0.9304 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7457.065 | 0.9374 | 0.9202 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7457.065 | 0.9025 | 0.8748 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7457.065 | 0.9762 | 0.9699 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7457.065 | 1.1352 | 1.1664 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7457.065 | 0.9513 | 0.9380 | 1.5870 | |
| HCC1954 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7457.065 | 0.8832 | 0.8494 | 1.5870 | |
| HCC202 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7458.065 | 1.0154 | 1.0632 | 0.4917 | |
| HCC202 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7458.065 | 1.0240 | 1.0987 | 0.4917 | |
| HCC202 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7458.065 | 1.0130 | 1.0533 | 0.4917 | |
| HCC202 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7458.065 | 0.9872 | 0.9482 | 0.4917 | |
| HCC202 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7458.065 | 1.0330 | 1.1363 | 0.4917 | |
| HCC202 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7458.065 | 0.9931 | 0.9720 | 0.4917 |