Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7449.065 | 1.0447 | 1.0426 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7449.065 | 1.0059 | 1.0057 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7449.065 | 0.6977 | 0.6817 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7449.065 | 1.0202 | 1.0194 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7449.065 | 1.0630 | 1.0597 | 2.0765 | |
| HCC1569 | HER2amp | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7449.065 | 0.9589 | 0.9600 | 2.0765 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7450.065 | 0.9288 | 0.9400 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7450.065 | 0.9099 | 0.9236 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7450.065 | 1.0295 | 1.0242 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7450.065 | 0.9444 | 0.9533 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7450.065 | 0.9703 | 0.9752 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7450.065 | 0.9827 | 0.9857 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7450.065 | 0.9714 | 0.9762 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7450.065 | 1.0234 | 1.0192 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7450.065 | 1.0221 | 1.0181 | 2.4231 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7451.065 | 0.9993 | 0.9994 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7451.065 | 0.9821 | 0.9833 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7451.065 | 1.0009 | 1.0008 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7451.065 | 0.9979 | 0.9980 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7451.065 | 0.9676 | 0.9696 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7451.065 | 0.9613 | 0.9637 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7451.065 | 0.9796 | 0.9809 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7451.065 | 0.9688 | 0.9708 | 2.1525 | |
| HCC1806 | TNBC | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7451.065 | 0.9496 | 0.9525 | 2.1525 | |
| HCC1937 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7453.065 | 0.9620 | 0.9540 | 1.6649 |