Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7492.065 | 0.9909 | 0.9887 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7492.065 | 1.0537 | 1.0663 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7492.065 | 0.9745 | 0.9681 | 1.6050 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7493.065 | 0.9940 | 0.9905 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7493.065 | 0.9733 | 0.9578 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7493.065 | 0.9550 | 0.9287 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7493.065 | 0.9597 | 0.9361 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7493.065 | 1.0038 | 1.0060 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7493.065 | 0.9685 | 0.9501 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7493.065 | 0.9972 | 0.9956 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7493.065 | 0.9783 | 0.9657 | 1.2680 | |
| MCF7 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7493.065 | 0.9969 | 0.9952 | 1.2680 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7494.065 | 0.9792 | 0.9381 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7494.065 | 0.9693 | 0.9089 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7494.065 | 0.9934 | 0.9803 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7494.065 | 0.9667 | 0.9012 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7494.065 | 0.9576 | 0.8746 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7494.065 | 0.9473 | 0.8446 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7494.065 | 0.9479 | 0.8462 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7494.065 | 0.9500 | 0.8524 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7494.065 | 1.0097 | 1.0290 | 0.6688 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 10419.065 | 0.9925 | 0.9795 | 0.7359 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 10419.065 | 1.0061 | 1.0167 | 0.7359 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 10419.065 | 0.9394 | 0.8371 | 0.7359 | |
| MDA-MB-134-VI | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 10419.065 | 0.9797 | 0.9449 | 0.7359 |