Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11851.144 | 0.9449 | 0.9190 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11851.144 | 0.9687 | 0.9542 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11851.144 | 0.9220 | 0.8849 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11851.144 | 0.9213 | 0.8839 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 11851.144 | 0.7604 | 0.6379 | 1.3716 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10875.144 | 0.9570 | 0.8903 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10875.144 | 0.9892 | 0.9722 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10875.144 | 1.0090 | 1.0232 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10875.144 | 0.9741 | 0.9336 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10875.144 | 0.9721 | 0.9286 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10875.144 | 0.9752 | 0.9364 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 10875.144 | 0.9519 | 0.8772 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 10875.144 | 0.8794 | 0.6956 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 10875.144 | 0.7240 | 0.3208 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12428.168 | 1.0228 | 1.0575 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12428.168 | 1.0432 | 1.1093 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12428.168 | 0.9910 | 0.9775 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12428.168 | 0.9984 | 0.9959 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12428.168 | 0.9925 | 0.9813 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12428.168 | 0.9742 | 0.9353 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12428.168 | 0.9449 | 0.8624 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12428.168 | 0.8488 | 0.6277 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 167 | uM | 12428.168 | 0.8589 | 0.6520 | 0.7957 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10819.144 | 0.9706 | 0.9735 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10819.144 | 0.8866 | 0.8951 | 2.2343 |