Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10819.144 | 0.9848 | 0.9864 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10819.144 | 0.9166 | 0.9236 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10819.144 | 0.9671 | 0.9703 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10819.144 | 0.9303 | 0.9364 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 10819.144 | 0.9426 | 0.9478 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 10819.144 | 0.7924 | 0.8022 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 10819.144 | 0.8264 | 0.8364 | 2.2343 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11937.144 | 0.9909 | 0.9925 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11937.144 | 0.9194 | 0.9320 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11937.144 | 1.0040 | 1.0033 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11937.144 | 1.0970 | 1.0777 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11937.144 | 0.9596 | 0.9664 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11937.144 | 0.9876 | 0.9898 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 11937.144 | 0.9726 | 0.9773 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 11937.144 | 0.7346 | 0.7616 | 2.4293 | |
| SUM149PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 11937.144 | 0.3206 | 0.2522 | 2.4293 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11057.144 | 1.0356 | 1.0186 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11057.144 | 1.1004 | 1.0513 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11057.144 | 1.0050 | 1.0026 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11057.144 | 1.1580 | 1.0792 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11057.144 | 0.8951 | 0.9422 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11057.144 | 1.0480 | 1.0250 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 11057.144 | 0.8675 | 0.9262 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 11057.144 | 0.3960 | 0.5651 | 3.7784 | |
| SUM159PT | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 11057.144 | 0.0085 | -0.4344 | 3.7784 |